Formulation of liquid soap incorporated with Mangifera indica (mango) leaf extracts and evaluation of its antibacterial activity against Staphylococcus spp.
CERYL GRACE B. HEMBRA, RYA CESSNA B. HENDERIN, MAUREEN COSETTE G. PAREÑAS, and RAMON ANGELO N. SINCO
Philippine Science High School – Western Visayas Campus, Brgy. Bito-on, Jaro, Iloilo City 5000, Department of Science and Technology, Philippines
After triclosan-containing soaps were banned by the United States Food and Drug Association due to health and environmental risk, the need for an alternative antibacterial agent arised. Leaves of Mangifera indica (mango) contain phytochemicals which promote antibacterial activity. This study aimed to determine whether M. indica leaves extract can be an alternative antibacterial agent for triclosan. There were three set-ups in this study namely formulated soaps with no antibacterial agent for soap base, triclosan, and M. indica extract. The set-ups were evaluated using the parameters pH, density, foam stability and free caustic alkali (FCA) along with antibacterial evaluation against Staphylococcus spp. Soap formulations passed the parameters except FCA. The antibacterial evaluation showed that soap with triclosan obtained the highest zone of inhibition (7.40±0.20 mm) followed by M. indica (6.87±0.06 mm). The results suggested that the formulated soap with M. indica extract cannot be used as an alternative to triclosan.
Keywords: triclosan, agar well diffusion method, hot saponification process, free caustic alkali, zone of inhibition